Biopharmaceuticals/Vaccine Experience

Case Studies

Project Profile: Vaccine Manufacturing Facility

Objective
Expand biologic facility in Canada for production of flu vaccines. The expansion is to be carried out in phases to support a three-fold increase in production capacity.

Capabilities
The expansion project includes expansion of the building footprint along with renovation of existing building areas, and additions/modifications to parking and landscaping. Production facilities include purification, formulation, filling/finishing, and packaging. Support systems include SIP/CIP systems, and modifications to existing clean steam and WFI systems. The facility is designed to EU Classifications B, C, and D (FDA Class 10,000 and 100,000).

Location
Canada

Size
New construction: 20,000 sq.ft
Renovated processing area: 8,000 sq.ft.
Renovated support area: 12,000 sq.ft.

Services
Process Engineering
Mechanical Engineering
Project Management
Compliance

Challenges
Processing technologies improved/developed concurrently with facility design, renovation and expansion within an operating facility, integrating activities of project team made up of IPS, local architect, local detailed engineer, GM and client.

Result
Compliant facility designed to meet client’s budget, with a phased project plan to bring the necessary capacity on-line without disrupting current operations.